Opportunities / DEPT OF DEFENSE
High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE)
| Notice type | Solicitation |
|---|---|
| Solicitation # | DARPA-PA-27-01 |
| Department | DEPT OF DEFENSE |
| Sub-tier / office | DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA) / DEF ADVANCED RESEARCH PROJECTS AGCY |
| NAICS | 541714 — Research and Development in Biotechnology (except Nanobiotechnology) |
| PSC | AC12 |
| Set-aside | None |
| Posted | Oct 28, 2026 |
| Response deadline | Nov 5, 2026 (2026-11-05T15:00:00) |
| Place of performance | — |
| Primary contact | Dr. Abhishek Singharoy, DARPA/BTO · HUBBLE@darpa.mil |
Description (excerpt)
UPDATE: The purpose of Amendment 1 to DARPA-PA-27-01, the HUBBLE Program Announcement (PA), is to update Attachment B and the verbiage in Section 4.1.2 and Section 7.8 of the Program Announcement. The Defense Advanced Research Projects Agency (DARPA) is soliciting proposals to develop an in-silico capability for mapping all protein-protein interactions. Utility of this capability will be demonstrated in identifying novel diagnostic and therapeutic targets within the interaction space underlying including traumatic brain injury.