Opportunities / DEPT OF DEFENSE

High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE)

Notice typeSolicitation
Solicitation #DARPA-PA-27-01
DepartmentDEPT OF DEFENSE
Sub-tier / officeDEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA) / DEF ADVANCED RESEARCH PROJECTS AGCY
NAICS541714 — Research and Development in Biotechnology (except Nanobiotechnology)
PSCAC12
Set-asideNone
PostedOct 28, 2026
Response deadlineNov 5, 2026 (2026-11-05T15:00:00)
Place of performance—
Primary contactDr. Abhishek Singharoy, DARPA/BTO · HUBBLE@darpa.mil

Description (excerpt)

UPDATE: The purpose of Amendment 1 to DARPA-PA-27-01, the HUBBLE Program Announcement (PA), is to update Attachment B and the verbiage in Section 4.1.2 and Section 7.8 of the Program Announcement. The Defense Advanced Research Projects Agency (DARPA) is soliciting proposals to develop an in-silico capability for mapping all protein-protein interactions. Utility of this capability will be demonstrated in identifying novel diagnostic and therapeutic targets within the interaction space underlying including traumatic brain injury.

View the official notice on SAM.gov →