Opportunities / DEPT OF DEFENSE

Non-Optical Methods for High Speed Protein Control

Notice typeSpecial Notice
Solicitation #DARPA-SN-26-89
DepartmentDEPT OF DEFENSE
Sub-tier / officeDEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA) / DEF ADVANCED RESEARCH PROJECTS AGCY
NAICS541714 — Research and Development in Biotechnology (except Nanobiotechnology)
PSCAC12
Set-asideNone
PostedJul 21, 2026
Response deadlineDec 31, 2026 (2026-12-31T23:59:00)
Place of performance—
Primary contactDr. Matthew Pava, DARPA/BTO · ERIS@darpa.mil

Description (excerpt)

UPDATE: The purpose of Amendment 1 to DARPA-SN-26-89, the Non-Optical Methods for High Speed Protein Control Special Notice (SN), is to clarify the notice deadline. DARPA BTO will be actively “shopping” the ERIS Marketplace for innovative, post-competitive, awardable solutions that address the need for a new class of rapidly switchable, non-optogenetic protein domains for real-time cellular control. This effort seeks to develop a robust and versatile molecular tool for massless information transfer across a cell membrane, intended to supplement existing synthetic biology platforms.

View the official notice on SAM.gov →